Barcoded Magnetic Bead
Technology:
Multiplex + Quantitative
Applied BioCode, Inc. (ABC) has combined
photolithographic digital barcodes with immuno-
and molecular chemistry to create a new,
patented Barcoded Magnetic Bead (BMB)
technology. This breakthrough technology is
designed to significantly improve the isolation
and identification capacity of in-vitro
diagnostics. The BMBs' barcode patterns give a
high-contrast transmitted signal and no
fluorescence background, allowing the barcode to
be identified easily and accurately, with near
100% decoding accuracy. Furthermore, because
the fluorescence is detected at steady state,
the variation of the fluorescence signal is
minimal, which is very important for
quantitative assays, such as protein analysis.
Bioassay
Protocols
Our Barcoded Magnetic Bead has one of the highest
multiplex capacities available (up
to 1,024 targets/assay). Optically
bar-coded beads are mass produced at low cost by
well established semiconductor processes. These
beads are functionalized with nucleic acids,
proteins or other probe molecules, allowing
highly multiplexed assays to be carried out in
homogeneous or heterogeneous media.
There are two analyzers, one for
an imaging-based
system
for low-to-medium multiplex assays
(up to
128-plex) and one for a
high multiplex
system
(up to 4,096-plex). Both BMB systems utilize the same bead
technology but will have different target
markets.
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